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Comments (32)
- amlutoDerek Lowe’s writeup is good: https://www.science.org/content/blog-post/progress-against-p...
- rvnxThe founders of Lovable and Builder.ai individually received more funds than the whole group of the researchers behind this medicine...
- StephenAmarIf you want to see what the side effects look like, look at ex Senator Ben Sasse: https://youtu.be/7CFo6-6BN9k?si=2B3dqB4rOhAnPiZl
- maxall4
- siva7> More than 90% of patients with the most common form of pancreatic cancer, pancreatic ductal adenocarcinoma (mPDAC), have a mutation in the Kras gene.So pancreatic cancer is basically a genetic disease for most patients instead of environmental?
- mrandishTotally naive question: is this a situation where stacking the drug with chemo might be even better?
- chilldsgnI hope they can get this to people quickly. Someone I love has been diagnosed with stage 3 end of Feb this year and it's utter hell. For everyone, not just the patient.
- ltbarcly3While it's a useful scientific achievement, and I am not second guessing any individuals decision, and any time is likely tempting to take if even to have time to make arrangements, this still only gives about 1 year survival on average to the scenario being quoted in the title, and that year is gruesomely painful.
- modzu"survival" is the wrong word; its terminal. honestly the drugs and chemo and treatments they put pancreatic patients through for possibly a few more (not very nice) weeks is almost criminal. a good doctor will tell you to go make the most of those 3 months post diagnosis. that said its nice to see progress against one of the worst cancers out there and i hope it leads to genuine breakthroughs. but this drug is nothing anybody wants, even if they think they do
- Herodotus38Source article for those interested:https://www.nejm.org/doi/full/10.1056/NEJMoa2505783Paywalled but has a free access option if you make an account.
- shevy-java[flagged]