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Comments (76)

  • armcat
    > the findings are not “a demonstration of a new antiaging treatment for people,”Regardless, every other study shows only positives of lifting and regular exercise, so just do it!
  • thisisauserid
    Soon we will have the technology to become mice and take advantage of the infinite wonders of these discoveries.
  • PowerElectronix
    It's always nice to get a new data point confirming that exercise and lifting is good your you, even better if it's through a new mechanism like this one.
  • saidnooneever
    do they release more when u break them because im great at that and people always guess my age way younger?
  • le-mark
    I’m probably too old to see any benefit from the coming anti aging treatments and societal turmoil. I’m ok with that. Getting old does suck though. The proteins in question are piezo1 and pigment epithelium-derived factor (PEDF).
  • chamomeal
    Thank you, bones
  • FemTech_AI
    I wonder how much older adults could benefit from adding simple squats or sit-to-stands to their daily walking routine.
  • Frieren
    If this were a mechanism that appeared under some kind of evolutionary pressure. What would that be? In which situations a normal mammal find its bones squished (but not crushed)? Or is it just a side effect of something else going on?
  • totetsu
    I’ll add a few season packs to my jellyfin and test the results. I don’t actually have to watch it though do I?
  • baud9600
    Right that’s it. Time to get a standing desk at work!
  • kilian_a
    Bonesqzr startup in here somewhere
  • anon
    undefined
  • adamgordonbell
    What are the proteins??
  • dude250711
    > Indeed, the research team could extend mouse lives by nearly 3 months—the equivalent of about nine human years—just by gently squeezing their leg bones.Assistant, your assignment for the next year is to give massages to these mice.But also, no need to exercise - just have something push on your bones gently all the time, right?
  • deadbabe
    This is only for mice, it has not been demonstrated in humans and the effect probably doesn’t scale up well.
  • 1up8192
    Somebody tell Brian Johnson all he needs is bones!
  • anon
    undefined
  • pezgordo
    I have to thanks gym bros on Instagram for making me start squating. Your legs are your biggest and strongest muscles, so even we ignore this research, they your biggest ally to control insulin/blood sugar.
  • riffraff
    Good thing I decided not to turn into a mollusk!
  • LoganDark
    One has to wonder what will become of cancer if aging is ever cracked. I really think cancer is the reason life evolved to have age. Because then most cancers can age rapidly and die out early, before they've taken their host with them. We still get cancers, but I would guess we'd get a lot more without age, and not just because we'd live longer.There are actually multiple forms of cancer that don't reactivate telomerase, and as a result age rapidly and die out on their own. Sometimes these are called pre-cancers, because they could still end up reactivating telomerase before they fully die, and then becoming a full cancer. A lot of them don't however, and a naïve solution to aging would remove this pre-cancer grace period entirely.
  • snvzz
    The mandatory Bone Song[0].0. https://www.youtube.com/watch?v=kHgRlsOvN3M
  • readthenotes1
    So in mice running doesn't do it but vice grips on the bones do?How would that translate to lifting weights or other exercises?
  • xlayn
    [dead]
  • imdsm
    So do we need to eat bones?